3et3
Structure of PPARgamma with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acidStructure of PPARgamma with 3-[5-Methoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-propionic acid
Template:ABSTRACT PUBMED 19116277
About this StructureAbout this Structure
3et3 is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Artis DR, Lin JJ, Zhang C, Wang W, Mehra U, Perreault M, Erbe D, Krupka HI, England BP, Arnold J, Plotnikov AN, Marimuthu A, Nguyen H, Will S, Signaevsky M, Kral J, Cantwell J, Settachatgull C, Yan DS, Fong D, Oh A, Shi S, Womack P, Powell B, Habets G, West BL, Zhang KY, Milburn MV, Vlasuk GP, Hirth KP, Nolop K, Bollag G, Ibrahim PN, Tobin JF. Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):262-7. Epub 2008 Dec 30. PMID:19116277
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OCACategories:
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- Histone acetyltransferase
- Homo sapiens
- Wang, W.
- Zhang, K Y.J.
- Activator
- Acyltransferase
- Adiponectin
- Alternative splicing
- Chromosomal rearrangement
- Diabetes
- Diabetes mellitus
- Disease mutation
- Dna-binding
- Drug discovery
- Fragment-based drug discovery
- Metabolic disease
- Metal-binding
- Nucleus
- Obesity
- Phosphoprotein
- Polymorphism
- Ppar
- Pparg
- Ppargamma
- Proto-oncogene
- Receptor
- Scaffold-based drug discovery
- Transcription
- Transcription regulation
- Transferase
- Ubl conjugation
- Zinc
- Zinc-finger