1ta2
Crystal structure of thrombin in complex with compound 1Crystal structure of thrombin in complex with compound 1
About this StructureAbout this Structure
1ta2 is a 2 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Tucker TJ, Brady SF, Lumma WC, Lewis SD, Gardell SJ, Naylor-Olsen AM, Yan Y, Sisko JT, Stauffer KJ, Lucas BJ, Lynch JJ, Cook JJ, Stranieri MT, Holahan MA, Lyle EA, Baskin EP, Chen IW, Dancheck KB, Krueger JA, Cooper CM, Vacca JP. Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position. J Med Chem. 1998 Aug 13;41(17):3210-9. PMID:9703466 doi:http://dx.doi.org/10.1021/jm9801713