Lamprey Variable Lymphocyte Receptor

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Template:STRUCTURE 3e6j

File:3e6j.png

Crystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharideCrystal Structure of Variable Lymphocyte Receptor (VLR) RBC36 in Complex with H-trisaccharide

Template:ABSTRACT PUBMED 18818359

About this StructureAbout this Structure

3E6J is a 1 chain structure of sequence from Petromyzon marinus. Full crystallographic information is available from OCA.

ReferencesReferences

[xtra 1]

  1. Han BW, Herrin BR, Cooper MD, Wilson IA. Antigen recognition by variable lymphocyte receptors. Science. 2008 Sep 26;321(5897):1834-7. PMID:18818359 doi:321/5897/1834

Additional LiteratureAdditional Literature

[xtra 1][xtra 2][xtra 3][xtra 4][xtra 5]

  1. Pancer Z, Amemiya CT, Ehrhardt GR, Ceitlin J, Gartland GL, Cooper MD. Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey. Nature. 2004 Jul 8;430(6996):174-80. PMID:15241406 doi:10.1038/nature02740
  2. Kim HM, Oh SC, Lim KJ, Kasamatsu J, Heo JY, Park BS, Lee H, Yoo OJ, Kasahara M, Lee JO. Structural diversity of the hagfish variable lymphocyte receptors. J Biol Chem. 2007 Mar 2;282(9):6726-32. Epub 2006 Dec 27. PMID:17192264 doi:10.1074/jbc.M608471200
  3. Mariuzza RA, Velikovsky CA, Deng L, Xu G, Pancer Z. Structural insights into the evolution of the adaptive immune system: the variable lymphocyte receptors of jawless vertebrates. Biol Chem. 2010 Jul;391(7):753-60. PMID:20482318 doi:10.1515/BC.2010.091
  4. Herrin BR, Cooper MD. Alternative adaptive immunity in jawless vertebrates. J Immunol. 2010 Aug 1;185(3):1367-74. PMID:20660361 doi:10.4049/jimmunol.0903128
  5. Liang J, Liu X, Wu FF, Li QW. [Progress of adaptive immunity system of agnathan vertebrates] Yi Chuan. 2009 Oct;31(10):969-76. PMID:19840917

External ResourcesExternal Resources

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Wayne Decatur, Michal Harel