User:Wayne Decatur/SandboxIppo

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This page, as it appeared on September 17, 2010, was featured in this article in the journal Biochemistry and Molecular Biology Education.

I-Ppo II-Ppo I

Homing Endonuclease

 

PDB ID 1a73

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I-Ppo bound to DNA (cleaved product) (1a73), resolution 1.8Å ().

[1][2]



I need to add back the Mg to the end of the morph and then remake these scene, or at least the User:Wayne_Decatur/SandboxIppo/1a73alonefrommorph/ view.

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  1. ↑ Flick KE, Jurica MS, Monnat RJ Jr, Stoddard BL. DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature. 1998 Jul 2;394(6688):96-101. PMID:9665136 doi:10.1038/27952
  2. ↑ Galburt EA, Chadsey MS, Jurica MS, Chevalier BS, Erho D, Tang W, Monnat RJ Jr, Stoddard BL. Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site. J Mol Biol. 2000 Jul 21;300(4):877-87. PMID:10891275 doi:10.1006/jmbi.2000.3874

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