1pv8
Crystal structure of a low activity F12L mutant of human porphobilinogen synthaseCrystal structure of a low activity F12L mutant of human porphobilinogen synthase
Template:ABSTRACT PUBMED 12897770
DiseaseDisease
Known disease associated with this structure: Porphyria, acute hepatic OMIM:[125270], Lead poisoning, susceptibility to OMIM:[125270]
About this StructureAbout this Structure
1PV8 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Breinig S, Kervinen J, Stith L, Wasson AS, Fairman R, Wlodawer A, Zdanov A, Jaffe EK. Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase. Nat Struct Biol. 2003 Sep;10(9):757-63. Epub 2003 Aug 3. PMID:12897770 doi:10.1038/nsb963
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