User talk:Johan sunryd/sandbox 1
Alpha-mannosidases I(ERMan1) is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
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Catalytic SiteCatalytic Site
The spinning protein () ) is a highlight of the catalytic residues of ERMan1.
"Molecular Playground banner: A catalytic timer for protein degradation."