User talk:Johan sunryd/sandbox 1

ER Man 1

Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.

spinqualitylabelsall models ERMan1 (1X9D) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Catalytic SiteCatalytic Site

The spinning protein () ) is a highlight of the catalytic residues of ERMan1.

Molecular Playground banner: A catalytic timer for protein degradation.