2fle

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Template:STRUCTURE 2fle

File:2fle.png

Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutantStructural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant

Template:ABSTRACT PUBMED 18215016

About this StructureAbout this Structure

2FLE is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Clemente JC, Robbins A, Grana P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J Med Chem. 2008 Feb 28;51(4):852-60. Epub 2008 Jan 24. PMID:18215016 doi:10.1021/jm701170f

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OCA

[1] Clemente JC, Robbins A, Grana P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J Med Chem. 2008 Feb 28;51(4):852-60. Epub 2008 Jan 24. PMID:18215016 doi:10.1021/jm701170f

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