Collagen Structure & Function

IntroductionIntroduction

Collagen is a member of a naturally occurring protein family. In nature is is found in animals and is responsible for a variety of biological functions.

Molecular StructureMolecular Structure

Collagen takes the form of a triple helix which is stabilized by hydrogen bonding. Each of it's alpha-helices are enclosed by a hydration cylinder. The molecule itself is approxiametly 1-2nm in diameter and 300nm in length.

Collagen-Related DisordersCollagen-Related Disorders

There are currently close to 30 different types of collagen that have been identified. The most abundant type of collagen present in the human body is that of Type I with significant amounts of Type II,III and IV also accounted for.

• Type I- found in bones,tendons,organs
• Type II-found mainly in cartilage
• Type III-found mainly in reticular fibres
• Type IV-found in the basement membrane of cell membranes
• Type V-found in hair

spinqualitylabelsall models PDB ID 1cag Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1cag, resolution 1.85Å ()
Ligands:
Non-Standard Residues:
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml