3in4

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File:3in4.jpg

Template:STRUCTURE 3in4

Bace1 with Compound 38Bace1 with Compound 38

Template:ABSTRACT PUBMED 20045648

About this StructureAbout this Structure

3IN4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Malamas MS, Barnes K, Johnson M, Hui Y, Zhou P, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Pangalos M, Reinhart P, Robichaud AJ. Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem. 2010 Jan 15;18(2):630-9. Epub 2009 Dec 6. PMID:20045648 doi:10.1016/j.bmc.2009.12.007

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