3hs4
Human carbonic anhydrase II complexed with acetazolamideHuman carbonic anhydrase II complexed with acetazolamide
Template:ABSTRACT PUBMED 19851004
DiseaseDisease
Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]
About this StructureAbout this Structure
3HS4 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Sippel KH, Robbins AH, Domsic J, Genis C, Agbandje-McKenna M, McKenna R. High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Oct 1;65(Pt, 10):992-5. Epub 2009 Sep 25. PMID:19851004 doi:10.1107/S1744309109036665
- ↑ Vidgren J, Liljas A, Walker NP. Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A. Int J Biol Macromol. 1990 Dec;12(6):342-4. PMID:2128470
Page seeded by OCA on Wed Dec 9 15:09:52 2009
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Carbonate dehydratase
- Homo sapiens
- Agbandje-McKenna, M.
- Domsic, J.
- Genis, C.
- McKenna, R.
- Robbins, A H.
- Sippel, K H.
- 4-thiadiazole-2-sulfonamide
- 5-acetamido-1
- Acetazolamide
- Acetylation
- Ca 2
- Ca ii
- Carbonic anhydrase 2
- Carbonic anhydrase ii
- Cytoplasm
- Disease mutation
- Lyase
- Metal-binding
- Polymorphism
- Zinc