Proteopedia:Table of Contents

INTRODUCTIONINTRODUCTION

• Introduction to the Chemistry of Life
• Water

BIOMOLECULESBIOMOLECULES

• Nucleotides, Nucleic Acids, and Genetic Information
  • Z-DNA
• Amino Acids
• Proteins: Primary Structure
• Proteins: Three-Dimensional Structure
• Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies
• Carbohydrates
• Lipids and Biological Membranes
• Membrane Transport

ENZYMESENZYMES

• Enzymatic Catalysis
  • Serine Hydrolases
    • Acetylcholinesterase (AChE)
      • Acetylcholine
      • Flexibility_of_aromatic_residues_in_acetylcholinesterase
      • AChE inhibitors and substrates
        • 1eve AChE-Aricept complex
• Enzyme Kinetics, Inhibition, and Control
• Biochemical Signaling

METABOLISMMETABOLISM

• Introduction to Metabolism
• Glucose Catabolism
• Glycogen Metabolism and Gluconeogenesis
• Citric Acid Cycle
• Electron Transport and Oxidative Phosphorylation
• Photosynthesis
• Lipid Metabolism
• Amino Acid Metabolism
• Mammalian Fuel Metabolism: Integration and Regulation

GENE EXPRESSION AND REPLICATIONGENE EXPRESSION AND REPLICATION

• Nucleotide Metabolism
• Nucleic Acid Structure
• DNA Replication, Repair, and Recombination
• Transcription and RNA Processing
• Protein Synthesis
• Regulation of Gene Expression

METHODS OF STRUCTURE DETERMINATIONMETHODS OF STRUCTURE DETERMINATION

• X-ray
  • X-ray_crystallography
  • SAXS
• NMR
• Electron Microscopy

METHODS OF STRUCTURE VISUALIZATION & MODELINGMETHODS OF STRUCTURE VISUALIZATION & MODELING

• Proteopedia
  • Teaching_Proteopedia
  • SAXS
• NMR
• Electron Microscopy