PISA

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Protein interfaces, surfaces and assemblies service PISA at European Bioinformatics Institute http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html, authored by Eugene Krissinel and Kim Henrick. Quoting from the PISA website: "PISA is an interactive tool for the exploration of macromolecular (protein, DNA/RNA and ligand) interfaces, prediction of probable quaternary structures (assemblies), database searches of structurally similar interfaces and assemblies, as well as searches on various assembly and PDB entry parameters."[1]

Biological units displayed in the 'Structure Box' on Proteopedia PDB entry pages (e.g. 1h88) are predictions of the most likely biological unit as calculated by PISA.

ReferencesReferences

  1. Krissinel E, Henrick K. Inference of macromolecular assemblies from crystalline state. J Mol Biol. 2007 Sep 21;372(3):774-97. Epub 2007 May 13. PMID:17681537 doi:10.1016/j.jmb.2007.05.022

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Eran Hodis