8x0f

Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and PAM VU29Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and PAM VU29

Structural highlights

8x0f is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 3.3Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GRM5_HUMAN Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.

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OCA