Proteopedia

8f4r

Gentamicin bound aminoglycoside efflux pump AcrDGentamicin bound aminoglycoside efflux pump AcrD

Structural highlights

8f4r is a 3 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 3.06Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACRD_ECOLI Participates in the efflux of aminoglycosides. Confers resistance to a variety of these substances.[1]

References

  1. ↑ Rosenberg EY, Ma D, Nikaido H. AcrD of Escherichia coli is an aminoglycoside efflux pump. J Bacteriol. 2000 Mar;182(6):1754-6. PMID:10692383 doi:10.1128/JB.182.6.1754-1756.2000

8f4r, resolution 3.06Å

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OCA
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