Crystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerensCrystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerens

Structural highlights

7xdr is a 18 chain structure with sequence from Marinobacter adhaerens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GGOP_MARAH Catalyzes the reversible phosphorolysis of 2-O-alpha-D-glucosylglycerol with retention of the anomeric configuration, forming alpha-D-glucose 1-phosphate and glycerol. Has most likely a catabolic role, either regulating the intracellular levels of glucosylglycerol, which acts as a compatible solute, or degrading it when the environmental conditions change. Cannot catalyze the phosphorolysis of sucrose or glucosylglycerate.[1]

References

  1. Franceus J, Decuyper L, D'hooghe M, Desmet T. Exploring the sequence diversity in glycoside hydrolase family 13_18 reveals a novel glucosylglycerol phosphorylase. Appl Microbiol Biotechnol. 2018 Apr;102(7):3183-3191. PMID:29470619 doi:10.1007/s00253-018-8856-1

7xdr, resolution 2.40Å

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