7ebf

Cryo-EM structure of Isocitrate lyase-1 from Candida albicansCryo-EM structure of Isocitrate lyase-1 from Candida albicans

Structural highlights

7ebf is a 4 chain structure with sequence from Candida albicans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron Microscopy, Resolution 2.63Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ACEA_CANAX Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate.[UniProtKB:P28240]

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OCA