6v0m

Sterile alpha-motif from apoptosis signal-regulating kinase 3Sterile alpha-motif from apoptosis signal-regulating kinase 3

6v0m is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.8Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

M3K15_HUMAN May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.^[1]

↑ Kaji T, Yoshida S, Kawai K, Fuchigami Y, Watanabe W, Kubodera H, Kishimoto T. ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells. Biochem Biophys Res Commun. 2010 Apr 30;395(2):213-8. doi:, 10.1016/j.bbrc.2010.03.164. Epub 2010 Apr 1. PMID:20362554 doi:http://dx.doi.org/10.1016/j.bbrc.2010.03.164