6elr

Human jak1 kinase domain in complex with compound 7Human jak1 kinase domain in complex with compound 7

Structural highlights

6elr is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
NonStd Res:
Activity:	Non-specific protein-tyrosine kinase, with EC number 2.7.10.2
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[JAK1_HUMAN] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

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OCA

6elr

Human jak1 kinase domain in complex with compound 7Human jak1 kinase domain in complex with compound 7

Structural highlights

Function

See Also

Contents

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