Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and Cmpd-4"Human squalene epoxidase (SQLE, squalene monooxygenase) structure with FAD and Cmpd-4"

Structural highlights

6c6n is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.3Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ERG1_HUMAN Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.

See Also

6c6n, resolution 2.30Å

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OCA