Proteopedia

6awg

Staphylococcus aureus Type II pantothenate kinase in complex with nucleotides and pantothenate analog Deoxy-N190PanStaphylococcus aureus Type II pantothenate kinase in complex with nucleotides and pantothenate analog Deoxy-N190Pan

Structural highlights

6awg is a 4 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

COAW_STAA8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.[1]

See Also

References

  1. ↑ Choudhry AE, Mandichak TL, Broskey JP, Egolf RW, Kinsland C, Begley TP, Seefeld MA, Ku TW, Brown JR, Zalacain M, Ratnam K. Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections. Antimicrob Agents Chemother. 2003 Jun;47(6):2051-5. PMID:12760898 doi:10.1128/AAC.47.6.2051-2055.2003

6awg, resolution 2.40Å

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OCA
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