Crystal structure of dihydropteroate synthase from Klebsiella pneumoniae subsp.Crystal structure of dihydropteroate synthase from Klebsiella pneumoniae subsp.

Structural highlights

5umg is a 2 chain structure with sequence from Klep7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:folP, KPN_03587 (KLEP7)
Activity:Dihydropteroate synthase, with EC number 2.5.1.15
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A6TEJ6_KLEP7] Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.[RuleBase:RU361205]

See Also

5umg, resolution 2.60Å

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OCA