5t15

Structural basis for gating and activation of RyR1 (30 uM Ca2+ dataset, all particles)Structural basis for gating and activation of RyR1 (30 uM Ca2+ dataset, all particles)

5t15, resolution 3.60Å Show:Asymmetric Unit Biological Assembly Structural highlights 5t15 is a 8 chain structure with sequence from Homo sapiens and Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.6Å Ligands: Experimental data: Check Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function FKB1B_HUMAN Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.