5lxj

Solution NMR structure of the X domain of Peste des Petits Ruminants phosphoproteinSolution NMR structure of the X domain of Peste des Petits Ruminants phosphoprotein

Structural highlights 5lxj is a 1 chain structure with sequence from Morbillivirus caprinae. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PHOSP_PPRV Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis (By similarity). Plays also a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication (By similarity). The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place (By similarity).[UniProtKB:P06162][UniProtKB:Q77M42]

spinqualitylabelsall models 5lxj Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image