4wr9

Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D)Crystal Structure of Surfactant Protein-A DED Mutant (E171D/P175E/K203D)

Structural highlights

4wr9 is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.301Å
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SFTPA_RAT In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

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OCA