4oew

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitorsCrystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

4oew is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3tsf. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.44Å
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDE5A_HUMAN Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

4oew

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitorsCrystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

Function

See Also

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)