3s4t

Crystal structure of putative amidohydrolase-2 (EFI-target 500288)from Polaromonas sp. JS666Crystal structure of putative amidohydrolase-2 (EFI-target 500288)from Polaromonas sp. JS666

Structural highlights

3s4t is a 8 chain structure with sequence from Polaromonas sp. JS666. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.9Å
Ligands:	, , , , ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GRDC_POLSJ Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (Probable). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:29283551). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, 2,4,6-trihydroxybenzoate to benzene-1,3,5-triol, and 2,6-dihydroxy-4-methylbenzoate to 5-methylbenzene-1,3-diol (PubMed:29283551).^[1]

References

↑ Sheng X, Patskovsky Y, Vladimirova A, Bonanno JB, Almo SC, Himo F, Raushel FM. Mechanism and Structure of γ-Resorcylate Decarboxylase. Biochemistry. 2018 Jun 5;57(22):3167-3175. PMID:29283551 doi:10.1021/acs.biochem.7b01213

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Sheng X, Patskovsky Y, Vladimirova A, Bonanno JB, Almo SC, Himo F, Raushel FM. Mechanism and Structure of γ-Resorcylate Decarboxylase. Biochemistry. 2018 Jun 5;57(22):3167-3175. PMID:29283551 doi:10.1021/acs.biochem.7b01213

[1]