3pwe

Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolutionCrystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution

Structural highlights

3pwe is a 2 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.199Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

DPO3B_ECOLI DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA.

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OCA

3pwe

Crystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolutionCrystal structure of the E. coli beta clamp mutant R103C, I305C, C260S, C333S at 2.2A resolution

Structural highlights

Function

See Also

Contents

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