Crystal Structure of the Vibrio cholerae Cytolysin (HlyA) Heptameric PoreCrystal Structure of the Vibrio cholerae Cytolysin (HlyA) Heptameric Pore

Structural highlights

3o44 is a 14 chain structure with sequence from Vibrio cholerae 12129(1). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.88Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HLYA_VIBCH Bacterial hemolysin that causes cytolysis by forming heptameric pores in target host membranes.[1]

See Also

References

  1. Olson R, Gouaux E. Crystal structure of the Vibrio cholerae cytolysin (VCC) pro-toxin and its assembly into a heptameric transmembrane pore. J Mol Biol. 2005 Jul 29;350(5):997-1016. PMID:15978620 doi:10.1016/j.jmb.2005.05.045

3o44, resolution 2.88Å

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