3D structures of human antibody

3D structures of Antibody3D structures of Antibody

Updated on 05-August-2020

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• Human Fab
  • 7fab, 1mco, 3na9, 3lrs, 3mme, 3hi5, 1vge, 3nfs, 1ad0, 3w9d, 4nm4, 8fab, 1opg, 4fnl, 4fqh, 6n32, 1aqk, 2hff, 2agj, 3hc0, 3g6a, 3dgg, 3dif, 1b2w, 3eyo, 3eyq, 2aj3, 3fzu, 3aaz, 3gje, 5fhb, 5fha, 5f6i, 5f6h, 5drw, 5d6c, 4py7, 4ptt, 4ob5, 5szf, 5chn, 4lkc, 4hie, 4gxv, 6u85 - hFab - human
    
  • 3naa, 3nab, 3nac, 3ncj, 3o2v, 3hc3, 3hc4 - hFab (mutant)
    
  • 6b0w, 6azx, 5bk5, 5bk3 - hFab anti-circumsporozoite
    
  • 6meg, 6med, 6mee, 6mef - hFab anti-hepacivirus
    
  • 6dzn, 5vz1 - hFab anti-ebola virus
    
  • 6nis - hFab anti-zika virus
    
  • 6phg, 6phh - hFab anti-malaria
    
  • 1rz7, 1rz8, 1rzf, 1rzg, 1rzi, 3mlj, 3mug, 3qeh, 3ttn, rpi, 3tnm, 4fz8, 4f58, 4f57, 4f5a, 5iie, 5dt1, 5cey, 5cex, 5cck, 5bzw, 5bzd, 4rqq, 5uy3, 4qf1, 6mtr, 6mts - hFab anti-HIV
    
• Human Fab: small molecule complex
  • 3o2w - hFab 1e9 (mutant) + transition state analog
    
  • 3oau – hFab 2g12 (mutant) + mannose
    
  • 4ptu, 4hih – hFab + rhamnose
    
  • 1ikf – hFab R45 + cyclosporin
    
  • 3oay, 3oaz, 3ob0, 6msy, 6mub, 6mu3, 6mnf - hFab 2g12 + glycan
    
  • 6n35, 6n2x, 5i8o - hFab + polysaccharide
    
• Human Fab: peptide complex
  • 3h0t - hFab + hepcidin peptide
    
  • 1sm3 - hFab SM3 + peptide
    
  • 5ea0 - hFab 7968 + complement factor peptide
    
  • 4z0x, 4xvj - hFab + HCV E2 peptide
    
  • 3eyf, 4hha – hFab + cytomegalovirus peptide
    
  • 2hfg, 2h9g – hFab + TNF receptor peptide
    
  • 3csy, 6n7j - hFab + Ebola envelope glycoprotein peptide
    
  • 4hs8, 5kzp – hFab + hepatitis virus peptide
    
  • 6b0s, 6azm, 5bk0, 6d11, 6d0x, 6d01 - hFab anti-circumsporozoite + circumsporozoite domain
    
  • 6h06, 6h0e, 6gk7, 6gk8, 5zia, 5zv3 - hFab + Tau peptide
    
  • 6mtp, 6mtt - hFab + HIV peptide
    
• Anti-HIV Fab: peptide complex
  • 3egs, 3drt, 3drq, 3dro, 2fx7, 2fx8, 2fx9, 2cmr, 1tzg, 1tjg, 3mnw, 3moa, 3mob, 3mod, 1tjh, 1tji, 1u8h, 1u8i, 1u8j, 1u8k, 1u8l, 1u8m, 1u8n, 1u8o, 1u8p, 1u8q, 1u91, 1u92, 1u93, 1u95, 2f5b, 3go1, 5drz, 4ydv - hFab anti-HIV + gp41 peptide
    
  • 3ghb, 3ghe, 3c2a - hFab anti-HIV + envelope glycoprotein peptide
    
  • 3fn0, 2oqj - hFab + peptide
    
  • 2b0s, 2b1a, 2b1h, 3se8, 3se9, 4jkp, 4jpv, 4jb9 - hFab anti-HIV + glycoprotein gp120 peptide
    
• Human Fab: protein complex
  • 3pnw – hFab + Tudor domain-containing protein 3
    
  • 3h42 - hFab LDLR + proprotein convertase subtilisin/kexin
    
  • 3nh7 – hFab ABD1556 + bone morphogenetic protein receptor
    
  • 3hi6 – hFab AL-57 + integrin
    
  • 2vxs, 5fhx - hFab + interleukin
    
  • 3b2u, 3b2v – hFab IMC-11F8 + EGFR
    
  • 2r0k, 2r0l – hFab + HGFA
    
  • 3be1, 3n85, 1n8z, 6att - hFab + ERBB-2
    
  • 6j71 - hmFab + ERBB-2
    
  • 3kr3 – hFab + IGF-II
    
  • 3g6d – hFab CNTO607 + IL-13
    
  • 3g6j – hFab + complement C3
    
  • 2wub, 3k2u – hFab 40 + hepatocyte growth factor activator
    
  • 3grw - hFab + fibroblast growth factor receptor
    
  • 6ba5 - hFab + tyrosine protein kinase receptor
    
  • 3bdy, 2qr0, 2fjg, 2fjh, 1cz8, 5fv2, 5fv1 – hFab + VEGF
    
  • 3bqu – hFab 2F5 anti-HIV + mFab 3H6
    
  • 1adq – hFab IGM + igG1 Fc
    
  • 3dvg, 3dvn – hFab igG1 + ubiquitin
    
  • 3bn9 – hFab E2 + membrane-type serine protease
    
  • 2jix – hFab ABT-007 + erythropoietin receptor
    
  • 1za3 - hFab YSD1 + TNF receptor
    
  • 3l95 – hFab + NRR1
    
  • 1uj3, 4dtg – hFab + tissue factor
    
  • 3lev – hFab 2F5 + RNA polymerase sigma factor
    
  • 3ru8, 6mto, 6mtq – hFab + scaffold
    
  • 3skj – hFab + ephrin receptor
    
  • 3sob – hFab + LPR6
    
  • 5kn5 - hFab + protransforming growth factor alpha
    
  • 5c8j – hFab + protein MJ0480
    
  • 4zso – hFab + natural cytotoxicity triggering receptor
    
  • 4rrp - hFab + ASF1P
    
  • 4qci - hFab + platelet factor B
    
  • 4mxv - hFab + lymphotoxin
    
  • 5dmj, 5ihl - hFab + CD40
    
  • 3vg9 – hFab + adenosine receptor
    
  • 3vga – hFab + adenosine receptor (mutant)
    
  • 2qqk, 2qql, 2qqn – hFab + neuropilin
    
  • 2vyr – hFab + MDM4
    
  • 6b0h, 6b0g, 6b0e, 6b0a, 6b08, 6azz - hFab + PFS25
    
  • 6aod, 6hhc - hFab + coagulation factor
    
  • 5oca - hFab + PCSK9
    
  • 5n88 - hFab + SFRS1-interacting protein
    
  • 5bk1, 5bjz - hFab + maltose-binding protein
    
  • 4hj0 - hFab + GIPR
    
  • 4g80, 4g7y, 4g7v - hFab + VSP
    
  • 6cyf – hFab + secretion system protein
    
  • 6cw3 – hFab + histone acetyltransferase
    
  • 6m58 – hFab + serum albumin
    
  • 6mvl – hFab + VISTA
    
  • 6nmr, 6nms, 6nmt, 6nmu, 6nmv – hFab + SIRP-alpha
    
  • 6o39 – hFab + frizzled-5
    
  • 6o3a, 6o3b – hFab + frizzled-7
    
  • 6phb, 6phc, 6phd, 6phf – hFab + PFS25
    
  • 6r0x – hFab + G6B
    
  • 6r2s – hFab + duffy receptor
    
  • 6u8c – hFab + protein G
    
  • 6xxv – hFab + S2_1.2
    
• Human Fab: viral protein complex
  • 6e3h, 6d0u, 5vag, 3gbm, 3gbn, 3lzf, 3fku, 3sdy, 3ztj, 3ztn, 4fp8, 4fqi, 4fqj, 4fqk, 4fql, 4fqr, 4fqv, 4fqy, 4gxu, 4nm8, 5gjt, 5gjs, 5dur, 5c0s, 4yk4, 4py8, 5wko, 5w6g, 5w0d, 5w08, 5v2a, 5umn, 5kaq, 6ml8, 6e56, 4r8w – hFab + Influenza virus hemagglutinin
    
  • 6pzy, 6pzz – hFab + Influenza virus neuraminidase
    
  • 5gzo, 5gzn, 6dfi, 6dfj, 5lcv – hFab + zika polyprotein
    
  • 5hj3, 5fhc – hFab + ebola envelope protein
    
  • 6dzm, 6uye – hFab + ebola spike proteins – Cryo EM
    
  • 6mej, 6meh, 6mei – hFab + hepacivirus glycoprotein
    
  • 5n09, 4utb, 4uta, 4ut9, 4ut6 – hFab + dengue virus envelope protein
    
  • 4c2i – hFab + dengue virus envelope protein - Cryo EM
    
  • 4dag – hFab + metapneumovirus glycoprotein F0
    
  • 6p91, 6p95 – hFab + lassa mammarenavirus glycoprotein
    
  • 6c6z, 4xak - hFab + coronavirus spike protein
    
  • 6z2m - hFab + coronavirus spike protein + nanobody
    
  • 7bwj - hFab + coronavirus receptor RBD
    
  • 6wps, 6wpt - hFab + coronavirus spike protein – Cryo EM
    
• Anti-HIV Fab: protein complex
  • 3mac, 3ma9 – hFab anti-HIV 8062 + transmembrane glycoprotein
    
  • 3idx, 3idy, 2ny7, 4jpw, 4lsp, 4lsq, 4lsr, 4lss, 4lst, 4lsu, 4lsv, 5te4, 5fyl, 5f9w, 5f96, 5f6j, 4ywg, 4ye4, 4ydl, 4ydk, 4ydj, 4ydi, 4yc2, 4ybl, 4s1s, 4s1r, 4s1q, 4rwy, 4rfn, 5w4l, 6w4m - hFab anti-HIV + gp120 core
    
  • 5v7j, 4j6r - hFab anti-HIV + gp160
    
  • 6pwu - hFab anti-HIV + gp160 – Cryo EM
    
  • 4xnz, 4xny, 4xmp - hFab anti-HIV + gp41
    
  • 6orn, 6oro, 6orp, 6orq - hFab anti-HIV + gp41 + gp120
    
  • 6ulc - hFab anti-HIV + gp41 + gp120 – Cryo EM
    
  • 6vpx - hFab anti-HIV + gp41 + gp120 + MPER peptide – Cryo EM
    
  • 5tfw, 5t85, 5t80, 5t6l, 5t5b, 5t29 - hFab anti-HIV + T117V2
    
  • 2x7l – hFab anti-HIV + HIV REV
    
• Human Fab: protein higher complexes
  • 2wuc - hFab 40 + hepatocyte growth factor activator + inhibitor
    
  • 3d85 - hFab 7G10 + IL-12 + IL-23
    
  • 4xwo - hFab + ATPase GET3 + Sec22
    
  • 4xvu - hFab + ATPase GET3 + NYV1
    
  • 4xtr - hFab + ATPase GET3 + PEP12P peptide
    
  • 4xmn - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85
    
  • 4xmm - hFab + Sec13 + Nup145 + Nup84 + Nup120 + Nup85 + SEH1
    
  • 4mxw - hFab + TNFR-III + lymphotoxin
    
  • 3bt2 – hFab anti-UPAR + urokinase-type plasminogen activator + vitronectin
    
  • 3gjf, 3hae – hFab + β-2-microglobulin + MHC antigen + NYESO peptide
    
  • 6gv4 – hFab + parechovirus proteins + RNA - Cryo EM
    
  • 6cw2 – hFab + histone acetyltransferase + transcriptional adapter
    
  • 6c5v – hFab + herpesvirus proteins - Cryo EM
    
  • 6c08 – hFab + amino acid transporter + Arg
    
• Human anti-HIV Fab: protein higher complexes
  • 1g9m, 1g9n, 1gc1, 2i5y, 2i60, 2nxy, 2nxz, 2ny0, 2ny1, 2ny2, 2ny3, 2ny4, 2ny5, 2ny6, 3jwd, 3jwo, 5a8h, 5a7x, 4r4h, 4h8w - hFab anti-HIV + envelope glycoprotein gp120 + CD4
    
  • 5jsa, 5js9, 5c7k, 5v8l, 5v8m - hFab anti-HIV + envelope glycoprotein gp120 + gp41
    
  • 4r4n, 4r4f - hFab anti-HIV + envelope glycoprotein gp120 + M48U1 peptide
    
  • 3lqa, 2qad - hFab anti-HIV + CD4 + gp41
    
• Full Immunoglobulin
  • 1hzh - hFab IgG B12
    
  • 1iga - hIgA1 - model
    
• Fc Fragments
  • 3dnk - hFc Igg1br />
  • 1qp1 – hFc BRE
    
  • 3muh – hFc PG9
    
  • 4bsv, 4bsw – hFc heterodimeric (mutant)
    
  • 1f6a - hFc IgE + high-affinity receptor Fc (ε) RI (α)
    
  • 1fp5 - hFc IgE C ε 3-C ε 4
    
• Fv Fragments
  • 3zhd, 3zhk, 3zhl – hFv scaffold
    
  • 4u3x – hFv + lysozyme
    
• Single chain variable fragment (scFv)
  • 6ehy, 6ehv, 6ehw, 6ehx, 5c2b, 5wym, 1x9q, 2a9m, 3kdm, 4buh, 3u6r, 3auv – hscFv
    
  • 4x4x, 6dn0, 2a9n – hscFv (mutant)
    
  • 3juy, 4ut7 – hscFv anti-HIV
    
• Single chain variable fragment complex
  • 5lbs – hscFv + zika envelope protein E
    
  • 5ljy – hscFv + Hantaan virus envelope protein
    
  • 6pcu – hscFv + rotavirus capsid protein
    
  • 5wn9 – hscFv + respiratory syncytial virus envelope protein
    
  • 4nik – hscFv + gankyrin
    
  • 5jz7 – hscFv + NGF
    
  • 4kv5 – hscFv + TGF
    
  • 2ybr, 2yc1 – hscFv + CN2 toxin
    
  • 5ujz, 5uk0, 5uk1, 5uk2 - hscFv + hemagglutinin – Cryo EM
    
  • 4v1d - hscFv + mammal toxin CN2
    
  • 5dhz, 5dhy, 5dhx, 5dhv – hscFv anti-HIV + HIV REV
    
• Single chain variable fragment complex with small molecule
  • 5j74, 5j75 – hscFv + inhibitor
    
  • 4lar – hscFv + dexedrine
    
  • 4las – hscFv + amphetamine derivative
    
  • 5yax – hscFv + HBV peptide
    
• Single domain antibody VHH or Camelid antibody or nanobody NB80
  • 5i0z, 5c6w – hVHH
    
  • 6cnw – hyVHH - hybrid
    
  • 6oan, 6oao – hVHH + DBP