Proteopedia

2ji5

Structure of UMP kinase from Pyrococcus furiosus complexed with UTPStructure of UMP kinase from Pyrococcus furiosus complexed with UTP

Structural highlights

2ji5 is a 2 chain structure with sequence from Pyrococcus furiosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.45Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PYRH_PYRFU Catalyzes the reversible phosphorylation of UMP to UDP, with ATP as the most efficient phosphate donor.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Marco-Marin C, Escamilla-Honrubia JM, Rubio V. First-time crystallization and preliminary X-ray crystallographic analysis of a bacterial-archaeal type UMP kinase, a key enzyme in microbial pyrimidine biosynthesis. Biochim Biophys Acta. 2005 Mar 14;1747(2):271-5. Epub 2004 Dec 9. PMID:15698963 doi:http://dx.doi.org/S1570-9639(04)00322-X

2ji5, resolution 2.45Å

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OCA
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