1m7w
HNF4a ligand binding domain with bound fatty acidHNF4a ligand binding domain with bound fatty acid
Structural highlights
FunctionHNF4A_RAT Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine. Evolutionary ConservationCheck, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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