3en4

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Template:STRUCTURE 3en4

File:3en4.png

Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP121, a multitargeted kinase inhibitorTargeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP121, a multitargeted kinase inhibitor

Template:ABSTRACT PUBMED 18849971

About this StructureAbout this Structure

3EN4 is a 2 chains structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117

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OCA

[1] Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117

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