Template:STRUCTURE 1zzr

File:1zzr.png

Rat nNOS D597N/M336V double mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide boundRat nNOS D597N/M336V double mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound

Template:ABSTRACT PUBMED 16285725

About this StructureAbout this Structure

1ZZR is a 2 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2]

  1. Li H, Flinspach ML, Igarashi J, Jamal J, Yang W, Gomez-Vidal JA, Litzinger EA, Huang H, Erdal EP, Silverman RB, Poulos TL. Exploring the binding conformations of bulkier dipeptide amide inhibitors in constitutive nitric oxide synthases. Biochemistry. 2005 Nov 22;44(46):15222-9. PMID:16285725 doi:http://dx.doi.org/10.1021/bi0513610
  2. Flinspach ML, Li H, Jamal J, Yang W, Huang H, Hah JM, Gomez-Vidal JA, Litzinger EA, Silverman RB, Poulos TL. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat Struct Mol Biol. 2004 Jan;11(1):54-9. Epub 2003 Dec 29. PMID:14718923 doi:http://dx.doi.org/10.1038/nsmb704

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