2ze1

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Template:STRUCTURE 2ze1

File:2ze1.jpg

X-ray structure of Bace-1 in complex with compound 6gX-ray structure of Bace-1 in complex with compound 6g

Template:ABSTRACT PUBMED 18162398

About this StructureAbout this Structure

2ZE1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets., Cole DC, Stock JR, Chopra R, Cowling R, Ellingboe JW, Fan KY, Harrison BL, Hu Y, Jacobsen S, Jennings LD, Jin G, Lohse PA, Malamas MS, Manas ES, Moore WJ, O'Donnell MM, Olland AM, Robichaud AJ, Svenson K, Wu J, Wagner E, Bard J, Bioorg Med Chem Lett. 2008 Feb 1;18(3):1063-6. Epub 2007 Dec 10. PMID:18162398

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