Structure of Mth11: A homologue of human RNase P protein Rpp29Structure of Mth11: A homologue of human RNase P protein Rpp29

Structural highlights

1oqk is a 1 chain structure with sequence from Methanothermobacter thermautotrophicus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RNP1_METTH Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.[1] [2]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Hall TA, Brown JW. Archaeal RNase P has multiple protein subunits homologous to eukaryotic nuclear RNase P proteins. RNA. 2002 Mar;8(3):296-306. PMID:12003490
  2. Boomershine WP, McElroy CA, Tsai HY, Wilson RC, Gopalan V, Foster MP. Structure of Mth11/Mth Rpp29, an essential protein subunit of archaeal and eukaryotic RNase P. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15398-403. Epub 2003 Dec 12. PMID:14673079 doi:10.1073/pnas.2535887100
Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA