2v3a
CRYSTAL STRUCTURE OF RUBREDOXIN REDUCTASE FROM PSEUDOMONAS AERUGINOSA.
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OverviewOverview
Crude oil spills represent a major ecological threat because of the, chemical inertness of the constituent n-alkanes. The Gram-negative, bacterium Pseudomonas aeruginosa is one of the few bacterial species able, to metabolize such compounds. Three chromosomal genes, rubB, rubA1, and, rubA2 coding for an NAD(P)H:rubredoxin reductase (RdxR) and two, rubredoxins (Rdxs) are indispensable for this ability. They constitute an, electron transport (ET) pathway that shuttles reducing equivalents from, carbon metabolism to the membrane-bound alkane hydroxylases AlkB1 and, AlkB2. The RdxR-Rdx system also is crucial as part of the oxidative stress, response in archaea or anaerobic bacteria. The redox couple has been, analyzed in detail as a model system for ET processes. We have solved the, structure ... [(full description)]
About this StructureAbout this Structure
2V3A is a [Single protein] structure of sequence from [Pseudomonas aeruginosa] with CL, FAD and PEG as [ligands]. Full crystallographic information is available from [OCA].
ReferenceReference
Crystal structure of the electron transfer complex rubredoxin rubredoxin reductase of Pseudomonas aeruginosa., Hagelueken G, Wiehlmann L, Adams TM, Kolmar H, Heinz DW, Tummler B, Schubert WD, Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12276-81. Epub 2007 Jul 16. PMID:17636129
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