Updated on 29-May-2023

1igs, 3tc6, 3tc7 – SsIGPS + PO4 – Sulfolobus solfataricus

    • 5aou – SsIGPS (mutant) + PO4
    • 5k7j – SsIGPS + Zn
    • 5an7 – SsIGPS + PO4 + inhibitor

1juk, 2c3z, 3nyz – SsIGPS + SO4

    • 6nw4 – SsIGPS + SO4 + nitrobenzotriazole

4iww – SsIGPS (mutant) + SO4 + Co

4ix0 – SsIGPS (mutant) + SO4 + Ni
1jul – SsIGPS
4a2r, 4a2s, 4a29 - SsIGPS TIM-barrel fold (mutant)

    • 1j5t, 2w6r – TmIGPS – Thermotoga maritima
    • 1i4n – TmIGPS + SO4
    • 4j9j – TmIGPS subunit HISF (mutant)
    • 1vh7, 2a0n – TmIGPS subunit HISF + PO4
    • 4fx7, 5tql, 6vdg – TmIGPS subunit HISF (mutant) + PO4
    • 3og3 – TmIGPS subunit HISF (mutant) + SO4
    • 3zr4 – TmIGPS subunits HISF+HISH + Gln
    • 6ymu – TmIGPS subunits HISF+HISH + Phe derivative
    • 6rtz, 6ru0 – TmIGPS subunits HISF+HISH + PO4
    • 2wjz – TmIGPS subunits HISF+HISH (mutant) + PO4

1vc4 – IGPS + SO4 – Thermus thermophilus

3qja – MtIGPS + SO4 – Mycobacterium tuberculosis
4fb7 – MtIGPS
3tsm – IGPS + SO4 – Brucella melitensis

    • 6bma – IGPS + PO4 – Campylobacter jejuni
    • 4gud – IGPS subunit HISH – Vibrio cholerae

IGPS complex with reactants or derivatives

    • 1ox4 – yIGPS HISHF amidotransferase+cyclase domains (mutant) + Ni + imidazole derivative

1a53 – SsIGPS + IGP

1lbf, 3nz1 – SsIGPS (mutant) + SO4 + transition state analog
3t40 – MtIGPS + CPG
3t44 – MtIGPS + IGP + anthranilate
3t55 – MtIGPS + PMBA
3t78 – MtIGPS + fluoroanthranilate
1jcm – EcIGPS N terminal + CDRP derivative – Escherichia coli

    • 4ewn – TmIGPS subunit HISF (mutant) + rCdRP
    • 6y88 – IGPS + rCdRP – Pseudomonas aeruginosa
  • Bifunctional IGPS/phosphoribosylanthrnilate isomerase (TRPC)
    • 7etx – CgTRPC – Corynebacterium glutamicum
    • 7ety – CgTRPC + CdRP

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Michal Harel