Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitorCrystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor

Structural highlights

5gv5 is a 8 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Triacylglycerol lipase, with EC number 3.1.1.3
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LIPB_PSEA2] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis.

5gv5, resolution 2.89Å

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OCA