Proteopedia

4nmh

Revision as of 09:22, 5 August 2016 by OCA (talk | contribs)

11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one

Structural highlights

4nmh is a 4 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:Hsd11b1, Hsd11 (LK3 transgenic mice)
Activity:11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DHI1_MOUSE] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.

See Also

4nmh, resolution 2.90Å

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