Alternative models for two crystal structures of Candida albicans 3,4-dihydroxy-2-butanone 4-phosphate synthase- alternate interpreationAlternative models for two crystal structures of Candida albicans 3,4-dihydroxy-2-butanone 4-phosphate synthase- alternate interpreation

Structural highlights

2riu is a 1 chain structure with sequence from candida_stellatoidea Atcc 11006 candida stellatoidea. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:RIB3 (ATCC 11006 Candida stellatoidea)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[RIB3_CANAL] Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity).[HAMAP-Rule:MF_00180]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Reinterpretation of the space-group symmetry is reported for two crystal structures of Candida albicans 3,4-dihydroxy-2-butanone 4-phosphate synthase (PDB codes 1tks and 1tku). The two structures reported in space group P1 with a dimer in the asymmetric unit can be described as C-centered monoclinic structures with one subunit in the asymmetric unit.

Alternative models for two crystal structures of Candida albicans 3,4-dihydroxy-2-butanone 4-phosphate synthase.,Le Trong I, Stenkamp RE Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):219-20. Epub 2008, Jan 16. PMID:18219123[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

  1. Le Trong I, Stenkamp RE. Alternative models for two crystal structures of Candida albicans 3,4-dihydroxy-2-butanone 4-phosphate synthase. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):219-20. Epub 2008, Jan 16. PMID:18219123 doi:10.1107/S0907444907056132

2riu, resolution 1.70Å

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