Crystal Structure of Human Glycine Receptor alpha-3 Bound to StrychnineCrystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine

Structural highlights

5cfb is a 5 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[GLRA3_HUMAN] The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

5cfb, resolution 3.04Å

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OCA