The crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulansThe crystal structure of 3-isopropylmalate dehydrogenase from Bacillus coagulans

Structural highlights

1v53 is a 2 chain structure with sequence from Atcc 7050. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:3-isopropylmalate dehydrogenase, with EC number 1.1.1.85
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[LEU3_BACCO] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1v53, resolution 2.85Å

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OCA