DeepView/Mutating Amino Acids

DeepView is a free molecular modeling program available for both Windows and OS X. Here are instructions for using DeepView to mutate an amino acid.

Caution: DeepView cannot predict changes in overall protein conformation after mutating amino acids, and it is unlikely that any existing program can do this reliably. Therefore, mutating one or more amino acids in an existing protein model will allow you to visualize the mutated sidechains in the context of the wild-type protein structure, but the resultating mutated model may not reflect changes that such mutations may induce in protein structure.

The following instructions were written for DeepView 4.1, current in May, 2015 (released October, 2012).