4c9f

Structure of SIGN-R1 in complex with SulfodextranStructure of SIGN-R1 in complex with Sulfodextran

Structural highlights

4c9f is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , ,
Resources:	FirstGlance, OCA, RCSB, PDBsum

Function

[C209B_MOUSE] Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

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OCA