2qp4

Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1

FunctionFunction

[ST2A1_HUMAN] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.

About this StructureAbout this Structure

2qp4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Lu LY, Hsieh YC, Liu MY, Lin YH, Chen CJ, Yang YS. Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1). Mol Pharmacol. 2008 Mar;73(3):660-8. Epub 2007 Nov 27. PMID:18042734 doi:10.1124/mol.107.041038

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OCA

[1] Lu LY, Hsieh YC, Liu MY, Lin YH, Chen CJ, Yang YS. Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1). Mol Pharmacol. 2008 Mar;73(3):660-8. Epub 2007 Nov 27. PMID:18042734 doi:10.1124/mol.107.041038

[xtra 1]