3psn
Crystal structure of mouse VPS29 complexed with Mn2+Crystal structure of mouse VPS29 complexed with Mn2+
FunctionFunction
[VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
About this StructureAbout this Structure
3psn is a 2 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 3lh7. Full crystallographic information is available from OCA.