3o2d

Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibodyCrystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody

FunctionFunction

[CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.

About this StructureAbout this Structure

3o2d is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017

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OCA

[1] Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017

[xtra 1]