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4bhb

Revision as of 23:23, 17 April 2013 by OCA (talk | contribs) (New page: {{STRUCTURE_4bhb| PDB=4bhb | SCENE= }} ===Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE=== {{ABSTRACT_PUBMED_23564173}} ==Function== [[http://www...)
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Template:STRUCTURE 4bhb

Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASECrystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE

Template:ABSTRACT PUBMED 23564173

FunctionFunction

[OGT_MYCTU] Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated (By similarity).

About this StructureAbout this Structure

4bhb is a 1 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

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