3tyq
SAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymeraseSAR development and discovery of potent indole-based inhibitors of the hepatitis c virus NS5B polymerase
About this StructureAbout this Structure
3tyq is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Chen KX, Lesburg CA, Vibulbhan B, Yang W, Chan TY, Venkatraman S, Velazquez F, Zeng Q, Bennett F, Anilkumar GN, Duca J, Jiang Y, Pinto P, Wang L, Huang Y, Selyutin O, Gavalas S, Pu H, Agrawal S, Feld B, Huang HC, Li C, Cheng KC, Shih NY, Kozlowski JA, Rosenblum SB, Njoroge FG. A Novel Class of Highly Potent Irreversible Hepatitis C Virus (HCV) NS5B Polymerase Inhibitors. J Med Chem. 2012 Jan 16. PMID:22247956 doi:10.1021/jm201322r